Event Details
Genome Stability and Instability:How Cells Repair Broken Chromosomes
Event Type:Lecture/Reading
Location: Cleveland L-1
Thursday, April 11, 2013
4:30 PM - 6:30 PM
Lectures & Symposia
Dianne Baranowski
Department:Biochemistry Department
Event Description:"GENOME STABILITY AND INSTABILITY: HOW CELLS REPAIR BROKEN CHROMOSOMES" James E. Haber, Ph.D., Professor of Biology, Brandeis University TEA AT 4:15 P.M. CLEVELAND LOBBY Double stranded breaks in the DNA are the most challenging for a cell to repair. The process of repairing a double strand break in a chromosome leads to an increased rates of mutagenesis, which can eventually lead to the formation of cancerous cells. Dr. Haber studies the repair of double strand breaks using genetic manipulation of the Saccharomyces cerevisiae (budding yeast) mating type switch system. This allows for the controlled formation of exactly one double stranded break in the yeast chromosome. These studies can then inform our understanding of the development of cancer.
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